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Skye Bioscience to Participate in Upcoming Investment and Medical Conferences

SAN DIEGO, Aug. 21, 2025 (GLOBE NEWSWIRE) -- Skye Bioscience, Inc. (Nasdaq: SKYE) (鈥淪kye鈥�), a clinical-stage biotechnology company focused on unlocking new therapeutic pathways for obesity and other metabolic health disorders, today announced that it will participate in the following upcoming investment and medical conferences:

Investment Conferences

• Cantor Global Healthcare Conference (New York)
  Fireside Chat Sept. 5 8:00 am ET + 1x1 meetings

• H.C. Wainwright Global Investment Conference (New York)
  Presentation Sept. 8 3:30 pm ET + 1x1 meetings

• Morgan Stanley Global Healthcare Conference (New York)
  Fireside Chat Sept. 10 7:00 am ET + 1x1 meetings

Medical/Scientific Conferences

• Obesity Science & Innovation (Boston)
  Keynote Panel Sept. 16 9:10 am ET
  Title: Pipeline priorities - exploring leading and emerging targets shaping the future of obesity therapeutics

• European Association for the Study of Diabetes Annual Meeting (EASD) (Vienna, Austria)
  Oral Presentation Sept. 19 10:15 am CET
  Title: A multiple dose study to evaluate the safety and tolerability of nimacimab, a peripherally restricted, inhibitory CB1 receptor antibody in subjects with metabolic associated fatty liver disease (MAFLD)

Available webcasts will be accessible on Skye鈥檚 .

About Skye Bioscience

Skye is focused on unlocking new therapeutic pathways for metabolic health through the development of next-generation molecules that modulate G-protein coupled receptors. Skye's strategy leverages biologic targets with substantial human proof of mechanism for the development of first-in-class therapeutics with clinical and commercial differentiation. Skye is conducting a Phase 2a clinical trial () in obesity for nimacimab, a negative allosteric modulating antibody that peripherally inhibits CB1. This study is also assessing the combination of nimacimab and a GLP-1R agonist (Wegovy庐). For more information, please visit: . Connect with us on and .

CONTACTS
Investor Relations

(858) 410-0266

LifeSci Advisors, Mike Moyer

(617) 308-4306

Media Inquiries
LifeSci Communications, Michael Fitzhugh

(628) 234-3889

FORWARD LOOKING STATEMENTS

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In some cases, forward-looking statements can be identified by terminology including 鈥渁nticipated,鈥� 鈥減lans,鈥� 鈥済oal,鈥� 鈥渇ocus,鈥� 鈥渁ims,鈥� 鈥渋ntends,鈥� 鈥渂elieves,鈥� 鈥渃an,鈥� 鈥渃ould,鈥� 鈥渃hallenge,鈥� 鈥減redictable,鈥� 鈥渨ill,鈥� 鈥渨ould,鈥� 鈥渕ay鈥� or the negative of these terms or other comparable terminology. These forward looking statements include, but are not limited to: (i) statements regarding the superior safety and tolerability profile of nimacimab relative to other small molecule CB1 inhibitors, (ii) statements relating to any expectations regarding the efficacy and therapeutic potential of nimacimab as a monotherapy or in combination with a GLP-1 targeted drug, including expectations based on preclinical DIO models, (iii) statements regarding nimacimab鈥檚 potential to change weight loss standards of care, (iv) statements regarding superior potency of nimacimab to other small molecule CB1 inhibitors based on nimacimab鈥檚 mechanism of action and (v) statements regarding the timing of receipt of final data from Skye鈥檚 Phase 2 obesity study of nimacimab. Such statements and other statements in this press release that are not descriptions of historical facts are forward-looking statements that are based on management鈥檚 current expectations and assumptions and are subject to risks and uncertainties. If such risks or uncertainties materialize or such assumptions prove incorrect, our business, operating results, financial condition, and stock price could be materially negatively affected. We operate in a rapidly changing environment, and new risks emerge from time to time. As a result, it is not possible for our management to predict all risks, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements the Company may make. Risks and uncertainties that may cause actual results to differ materially include, among others, our capital resources, uncertainty regarding the results of future testing and development efforts and other risks that are described in the Company鈥檚 periodic filings with the Securities and Exchange Commission, including in the 鈥淩isk Factors鈥� section of Skye鈥檚 most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q. Except as expressly required by law, Skye disclaims any intent or obligation to update these forward-looking statements.