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SINTX Technologies Publishes Landmark Study Demonstrating Broad-Spectrum Antiviral Activity of Silicon Nitride

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SINTX Technologies (NASDAQ: SINT) has published groundbreaking research demonstrating its silicon nitride (Si₃N�) material's powerful antiviral properties against multiple virus strains, including SARS-CoV-2 and MERS-CoV. The study showed up to 99.97% reduction in SARS-CoV-2 within 10 minutes of contact.

As the only FDA-cleared and ISO-certified silicon nitride manufacturer in the U.S., SINTX is targeting the infection-prevention market, estimated to reach $230 billion by 2032. The company aims to commercialize applications in wound care, surgical equipment, PPE, and medical textiles. Silicon nitride offers advantages over traditional antimicrobials, being non-toxic to mammalian cells while effectively neutralizing pathogens.

SINTX Technologies (NASDAQ: SINT) ha pubblicato ricerche rivoluzionarie che dimostrano le potenti proprietà antivirali del suo materiale in nitruro di silicio (Si₃N�) contro più ceppi virali, inclusi SARS-CoV-2 e MERS-CoV. Lo studio ha rilevato una riduzione fino al 99,97% di SARS-CoV-2 entro 10 minuti di contatto.

Unica negli Stati Uniti come produttrice di nitruro di silicio approvata dalla FDA e certificata ISO, SINTX si rivolge al mercato della prevenzione delle infezioni, stimato raggiungere 230 miliardi di dollari entro il 2032. L'azienda punta a commercializzare applicazioni in cura delle ferite, strumenti chirurgici, DPI e tessuti medici. Il nitruro di silicio presenta vantaggi rispetto agli antimicrobici tradizionali: è non tossico per le cellule dei mammiferi ma efficace nel neutralizzare i patogeni.

SINTX Technologies (NASDAQ: SINT) ha publicado una investigación pionera que demuestra las potentes propiedades antivirales de su material de nitruro de silicio (Si₃N�) frente a múltiples cepas virales, incluyendo SARS-CoV-2 y MERS-CoV. El estudio mostró hasta un 99,97% de reducción de SARS-CoV-2 en 10 minutos de contacto.

Como la única fabricante estadounidense de nitruro de silicio autorizada por la FDA y certificada por ISO, SINTX se orienta al mercado de prevención de infecciones, estimado en 230 000 millones de dólares para 2032. La compañía pretende comercializar aplicaciones en cuidado de heridas, instrumental quirúrgico, EPI y textiles médicos. El nitruro de silicio ofrece ventajas frente a los antimicrobianos tradicionales: no es tóxico para las células de mamíferos y neutraliza eficazmente a los patógenos.

SINTX Technologies (NASDAQ: SINT)� 질화규소(Si₃N�) 소재가 SARS-CoV-2와 MERS-CoV� 포함� 여러 바이러스 균주� 대� 강력� 항바이러� 특성� 보인다는 획기적인 연구 결과� 발표했습니다. 연구에서� 접촉 10� 이내� SARS-CoV-2� 최대 99.97% 감소싵Ӽ습니�.

미국에서 유일하게 FDA 승인 � ISO 인증� 받은 질화규소 제조업체� SINTX� 감염 예방 시장� 목표� 하고 있으�, � 시장은 2032년까지 2,300� 달러� 이를 것으� 추정됩니�. 회사� 상처 치료, 수술 기구, 개인 보호 장비(PPE) � 의료� 섬유 분야� 상용화를 추진하고 있습니다. 질화규소� 포유� 세포� 무독성이면서� 병원체를 효과적으� 무력화하� � 기존 항미생물제보� 장점� 있습니다.

SINTX Technologies (NASDAQ: SINT) a publié des recherches révolutionnaires démontrant les puissantes propriétés antivirales de son matériau en nitrure de silicium (Si₃N�) contre plusieurs souches virales, dont SARS-CoV-2 et MERS-CoV. L'étude a montré une réduction allant jusqu'à 99,97 % de SARS-CoV-2 après 10 minutes de contact.

Seule fabricante américaine de nitrure de silicium approuvée par la FDA et certifiée ISO, SINTX vise le marché de la prévention des infections, estimé à 230 milliards de dollars d'ici 2032. La société prévoit de commercialiser des applications pour les soins des plaies, les instruments chirurgicaux, les EPI et les textiles médicaux. Le nitrure de silicium présente des avantages par rapport aux antimicrobiens traditionnels : il n'est pas toxique pour les cellules des mammifères tout en neutralisant efficacement les agents pathogènes.

SINTX Technologies (NASDAQ: SINT) hat wegweisende Forschung veröffentlicht, die zeigt, dass sein Siliziumnitrid-Material (Si₃N�) starke antivirale Eigenschaften gegenüber mehreren Virus-Stämmen, darunter SARS-CoV-2 und MERS-CoV, besitzt. Die Studie ergab eine Reduktion von bis zu 99,97% bei SARS-CoV-2 binnen 10 Minuten Kontaktzeit.

Als einziges in den USA FDA-zugelassener und ISO-zertifizierter Hersteller von Siliziumnitrid zielt SINTX auf den Markt zur Infektionsprävention, der bis 2032 auf 230 Milliarden US-Dollar geschätzt wird. Das Unternehmen plant die Kommerzialisierung für Wundversorgung, chirurgische Instrumente, PSA und medizinische Textilien. Siliziumnitrid bietet Vorteile gegenüber herkömmlichen antimikrobiellen Mitteln: es ist für Säugetierzellen nicht toxisch, neutralisiert jedoch effektiv Krankheitserreger.

Positive
  • Demonstrated 99.97% reduction in SARS-CoV-2 within 10 minutes of contact
  • Targeting massive $230 billion infection-prevention market by 2032
  • Only FDA-cleared and ISO-certified silicon nitride manufacturer in the U.S.
  • Superior safety profile compared to traditional metal-based antimicrobials
  • Multiple potential commercial applications in high-value medical markets
Negative
  • Company transitioning from single-product focus, indicating execution risks
  • Commercialization timeline and market adoption rates uncertain
  • Will require partnerships and licensing deals to accelerate growth

Insights

SINTX's silicon nitride shows impressive antiviral properties, opening substantial commercial opportunities beyond orthopedics into infection control markets.

The publication of this peer-reviewed study represents a significant scientific validation for SINTX Technologies' silicon nitride (Si₃N�) material. The data showing 99.97% reduction of infectious SARS-CoV-2 within 10 minutes and complete inactivation by 30 minutes is remarkably potent for a non-pharmaceutical intervention. More impressively, the 97% inactivation rate when embedded in textiles suggests practical commercial applications are feasible.

What makes this particularly notable is the mechanism of action—silicon nitride releases reactive nitrogen species that damage viral RNA and proteins without harming mammalian cells at therapeutic levels. This provides a critical advantage over metal-based antimicrobials like silver or copper, which can present toxicity concerns. The broad-spectrum activity against multiple coronavirus variants further strengthens its potential utility.

The scientific significance extends beyond the immediate findings. As the only FDA-cleared and ISO-certified silicon nitride manufacturer in the U.S., SINTX has positioned itself with significant regulatory advantages. This creates substantial barriers to entry for competitors while facilitating faster commercialization pathways for SINTX.

This research effectively transforms SINTX from a niche orthopedic implant company into a platform technology enterprise with applications spanning medical textiles, PPE, and wound care—addressing a projected $230 billion market by 2032. The combination of proven efficacy, regulatory clearance, and manufacturing capability gives SINTX legitimate opportunities to capture meaningful market share in these high-growth segments.

Breakthrough findings open doors to multi-billion-dollar infection-control markets

SALT LAKE CITY, Utah, Sept. 03, 2025 (GLOBE NEWSWIRE) -- SINTX Technologies, Inc. (NASDAQ: SINT) (“SINTX� or the “Company�), an advanced ceramics innovator specializing in biomedical applications of silicon nitride (Si₃N�), today announced the publication of a peer-reviewed study demonstrating that silicon nitride exhibits potent antiviral activity against multiple infectious virus strains, including SARS-CoV-2 and MERS-CoV.

The study, conducted in collaboration with Professor Kylene Kehn-Hall’s group at Virginia Polytechnic Institute and State University (Virginia Tech), further strengthens the evidence for using silicon nitride in a wide range of infection-control applications.

A Unique Infection-Control Platform

Building on its legacy as the only FDA-cleared and ISO-certified silicon nitride manufacturer, SINTX is positioning its proprietary material as a next-generation infection-prevention additive with potential applications in:

  • Wound dressings that inhibit infection and accelerate healing.
  • Surgical sutures with antimicrobial surfaces to reduce bacterial colonization.
  • Face masks and respirators with embedded antiviral protection.
  • Hospital linens and gowns offering continuous surface protection.
  • HEPA filters capable of capturing and inactivating airborne pathogens.

“This study confirms that silicon nitride is much more than a high-performance implant material—it’s a safe, effective, and broad-spectrum antiviral platform,� said Dr. Ryan Bock, Chief Technology Officer of SINTX Technologies and co-author of the study. “Its ability to inactivate dangerous viruses in minutes could transform how we approach infection prevention in healthcare and beyond.�

Study Findings

The study demonstrated that direct contact to alpha-phase silicon nitride (α-Si₃N�) reduced infectious SARS-CoV-2 titers by up to 99.97% within 10 minutes and complete inactivation observed by 30 minutes. In addition, 97% inactivation with contact to Si₃N� when embedded in textile fabric widely used in a variety of medical devices and PPE products. The material also demonstrated similar broad-spectrum virucidal activity against several SARS-CoV-2 variants and MERS-CoV, with minimal cytotoxicity in mammalian cell cultures.

“These results arrive at a time when healthcare systems are actively seeking sustainable solutions to prevent future pandemics, combat antimicrobial resistance, and reduce healthcare-associated infections,� said Eric Olson, Chief Executive Officer of SINTX Technologies. “As the only U.S.-based FDA-cleared and ISO-certified silicon nitride manufacturer, we are uniquely positioned to commercialize this technology in high-value markets where safety, efficacy, and scalability matter.�

Potential Market Opportunity

The global infection-prevention and control market, encompassing medical textiles, antimicrobial wound care, and PPE, is projected to exceed $230 billion by 2032 (source: Precedence Research). The antiviral PPE market alone is estimated to reach $40+ billion by 2030, while the global wound care market is forecast to surpass $30 billion by 2030 (sources: Grand View Research, Fortune Business Insights). SINTX believes silicon nitride-based products can capture significant market share in these sectors due to their superior safety profile and performance compared to traditional metal-based antimicrobials.

Advantages Over Traditional Antimicrobials

Unlike copper, silver, or zinc additives—which may raise toxicity or environmental concerns—silicon nitride releases reactive nitrogen species such as ammonia and nitric oxide that are non-toxic to mammalian cells at therapeutic levels. These species damage viral RNA and proteins, rendering pathogens non-infectious without harming surrounding tissue.

Positioning for Growth

The publication marks a strategic milestone as SINTX transitions from a single-product orthopedic implant manufacturer to a platform technology company with broad applications in infection control, advanced materials, and medical devices. The company is actively pursuing partnerships and licensing opportunities to accelerate commercialization.

The full study, “Antiviral Efficacy of Silicon Nitride Against SARS-CoV-2 and MERS-CoV: Implications for PPE Innovation�, is available online through Frontiers in Microbiology

About SINTX Technologies, Inc.

Located in Salt Lake City, Utah, SINTX Technologies is an advanced ceramics company that develops and commercializes materials, components, and technologies for medical and agribiotech applications. SINTX is a global leader in the research, development, and manufacturing of silicon nitride, and its products have been implanted in humans since 2008. Over the past several years, SINTX has utilized strategic acquisitions and alliances to enter new markets. For more information on SINTX Technologies or its materials platform, visit .

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 (“PSLRA�) that are subject to a number of risks and uncertainties. Forward-looking statements include statements regarding SINTX Technologies� expectations, beliefs, plans, strategies, potential applications, commercialization efforts, future market opportunities, and positioning for growth. These forward-looking statements include statements regarding: the potential for silicon nitride to serve as a next-generation infection-prevention additive; anticipated applications in wound dressings, surgical sutures, face masks, respirators, hospital linens, gowns, and HEPA filters; the Company’s belief that its technology can transform infection prevention; its plans to commercialize silicon nitride-based products and capture market share; the Company’s transition to a platform technology company; and its pursuit of partnerships and licensing opportunities to accelerate commercialization. Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied. These risks and uncertainties include, but are not limited to, the Company’s ability to successfully develop, manufacture, and commercialize new products; regulatory approvals; competition; market acceptance; intellectual property protection; and other factors described in the Company’s Risk Factors disclosure in its Annual Report on Form 10-K, filed with the SEC on March 19, 2025, and in its other filings with the Securities and Exchange Commission. SINTX undertakes no obligation to update or revise any forward-looking statements to reflect events or circumstances after the date of this press release, except as required by law.

Business and Media Inquiries for SINTX:

Elliot Sloane
ThroughCo Communications

917-291-0833

Katie Russo
ThroughCo Communications

501-282-5069

SINTX Technologies, Inc.
801.839.3502


FAQ

What were the key findings of SINTX Technologies' antiviral study for silicon nitride?

The study showed that silicon nitride (Si₃N�) reduced infectious SARS-CoV-2 titers by 99.97% within 10 minutes and achieved complete inactivation by 30 minutes. It also demonstrated 97% inactivation when embedded in textile fabric.

What is the market potential for SINTX Technologies' silicon nitride technology?

The global infection-prevention market is projected to exceed $230 billion by 2032, with the antiviral PPE market reaching $40+ billion by 2030 and the wound care market surpassing $30 billion by 2030.

How does SINTX's silicon nitride compare to traditional antimicrobial materials?

Unlike copper, silver, or zinc additives, silicon nitride releases non-toxic reactive nitrogen species that damage viral RNA and proteins without harming surrounding tissue or raising toxicity concerns.

What are the potential commercial applications for SINTX Technologies' silicon nitride?

Applications include wound dressings, surgical sutures, face masks, respirators, hospital linens, gowns, and HEPA filters for infection prevention and control.

What is SINTX Technologies' current market position in silicon nitride manufacturing?

SINTX is the only U.S.-based FDA-cleared and ISO-certified silicon nitride manufacturer, positioning them uniquely for commercialization in regulated medical markets.
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Medical Devices
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United States
SALT LAKE CITY