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STOCK TITAN

[Form 4] Centessa Pharmaceuticals plc American Insider Trading Activity

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
4
Rhea-AI Filing Summary

Centessa Pharmaceuticals plc (CNTA) � Form 4 insider filing

Director Brett I. W. Zbar reported the grant of an option to acquire 40,000 ordinary shares of Centessa Pharmaceuticals on 20 June 2025 at an exercise price of $12.43 per share. The instrument is classified as a “Share Option (right to buy)� and is held directly.

The option vests in full on the earlier of (i) the first anniversary of 20 June 2025 or (ii) the Company’s next annual meeting of shareholders, subject to Dr. Zbar’s continued service as director. The option carries a 10-year term with an expiration date of 20 June 2035. Following the grant, Dr. Zbar reports beneficial ownership of 40,000 derivative securities and no change to non-derivative share ownership was disclosed.

The filing notes that the option is held by Dr. Zbar solely for the benefit of General Atlantic Service Company, L.P.; he disclaims beneficial ownership except to the extent of any pecuniary interest.

No open-market purchases or sales of CNTA ordinary shares or ADSs were reported, and the filing does not indicate transactions made under a Rule 10b5-1 plan.

Centessa Pharmaceuticals plc (CNTA) � Comunicazione interna Form 4

Il direttore Brett I. W. Zbar ha segnalato la concessione di un'opzione per acquisire 40.000 azioni ordinarie di Centessa Pharmaceuticals con scadenza il 20 giugno 2025 ad un prezzo di esercizio di $12,43 per azione. Lo strumento è classificato come “Opzione su azioni (diritto di acquisto)� ed è detenuto direttamente.

L'opzione matura completamente alla prima delle seguenti date: (i) il primo anniversario del 20 giugno 2025 oppure (ii) la successiva assemblea annuale degli azionisti della Società, subordinatamente alla continuazione del servizio del dott. Zbar come direttore. L'opzione ha una durata di 10 anni con scadenza il 20 giugno 2035. Dopo la concessione, il dott. Zbar dichiara la proprietà beneficiaria di 40.000 strumenti derivati senza variazioni nella proprietà diretta delle azioni ordinarie.

Il documento specifica che l'opzione è detenuta dal dott. Zbar esclusivamente per conto di General Atlantic Service Company, L.P.; egli rinuncia alla proprietà beneficiaria salvo per l'interesse pecuniario eventualmente detenuto.

Non sono stati segnalati acquisti o vendite sul mercato aperto di azioni ordinarie CNTA o ADS, né la comunicazione indica transazioni effettuate nell'ambito di un piano Rule 10b5-1.

Centessa Pharmaceuticals plc (CNTA) � Declaración interna Formulario 4

El director Brett I. W. Zbar reportó la concesión de una opción para adquirir 40,000 acciones ordinarias de Centessa Pharmaceuticals con fecha 20 de junio de 2025 a un precio de ejercicio de $12.43 por acción. El instrumento está clasificado como “Opción sobre acciones (derecho a compra)� y se mantiene directamente.

La opción se consolida completamente en la primera de las siguientes fechas: (i) el primer aniversario del 20 de junio de 2025 o (ii) la próxima junta anual de accionistas de la Compañía, condicionada al servicio continuo del Dr. Zbar como director. La opción tiene un plazo de 10 años con fecha de vencimiento el 20 de junio de 2035. Tras la concesión, el Dr. Zbar reporta la propiedad beneficiaria de 40,000 valores derivados sin cambios en la propiedad directa de acciones ordinarias.

El documento señala que la opción es mantenida por el Dr. Zbar únicamente en beneficio de General Atlantic Service Company, L.P.; él renuncia a la propiedad beneficiaria excepto en la medida de cualquier interés pecuniario.

No se reportaron compras o ventas en mercado abierto de acciones ordinarias CNTA o ADS, ni el formulario indica transacciones realizadas bajo un plan Rule 10b5-1.

Centessa Pharmaceuticals plc (CNTA) � 내부� 신고� Form 4

이사 Brett I. W. Zbar� 2025� 6� 20일에 Centessa Pharmaceuticals� 보통� 40,000주를 취득� � 있는 옵션 부�주당 행사 가� $12.43� 보고했습니다. � 권리� '주식 옵션(매수 권리)'으로 분류되며 직접 보유하고 있습니다.

옵션은 (i) 2025� 6� 20일의 1주년 또는 (ii) 회사� 다음 연례 주주총회 � 빠른 날짜� 완전� 취득되며, 이는 Zbar 박사� 이사� 지� 근무� 조건으로 합니�. 옵션� 유효 기간은 10�이며 만료일은 2035� 6� 20일입니다. 부� � Zbar 박사� 40,000개의 파생 증권� 대� 실질 소유�� 보고했으�, 비파� 주식 소유권에� 변동이 없었습니�.

신고서에� � 옵션� Zbar 박사� 의해 General Atlantic Service Company, L.P.� 이익� 위해서만 보유되며, 금전� 이해관계가 있는 범위� 제외하고� 실질 소유권을 부인한다고 명시되어 있습니다.

CNTA 보통주나 ADS� 공개 시장 매수 또는 매도� 보고되지 않았으며, Rule 10b5-1 계획� 따른 거래� 언급되지 않았습니�.

Centessa Pharmaceuticals plc (CNTA) � Déclaration d’initié Formulaire 4

Le directeur Brett I. W. Zbar a déclaré la concession d’une option d’achat de 40 000 actions ordinaires de Centessa Pharmaceuticals au 20 juin 2025 à un prix d’exercice de 12,43 $ par action. L’instrument est classé comme une « Option d’achat d’actions » et est détenu directement.

’oپDz devient entièrement acquise à la première des dates suivantes : (i) le premier anniversaire du 20 juin 2025 ou (ii) la prochaine assemblée générale annuelle de la Société, sous réserve du maintien du service du Dr Zbar en tant que directeur. ’oپDz a une durée de 10 ans avec une date d’expiration au 20 juin 2035. Suite à la concession, le Dr Zbar déclare une propriété bénéficiaire de 40 000 titres dérivés sans changement dans la détention d’actions ordinaires non dérivées.

Le document précise que l’option est détenue par le Dr Zbar uniquement au bénéfice de General Atlantic Service Company, L.P. ; il décline la propriété bénéficiaire, sauf dans la mesure d’un intérêt pécuniaire éventuel.

Aucun achat ou vente sur le marché ouvert d’actions ordinaires CNTA ou d’ADS n’a été signalé, et la déclaration n’indique pas de transactions réalisées dans le cadre d’un plan Rule 10b5-1.

Centessa Pharmaceuticals plc (CNTA) � Insider-Meldung Form 4

Direktor Brett I. W. Zbar meldete die Gewährung einer Option zum Erwerb von 40.000 Stammaktien von Centessa Pharmaceuticals am 20. Juni 2025 zu einem Ausübungspreis von $12,43 pro Aktie. Das Instrument ist als „Aktienoption (Kaufrecht)� klassifiziert und wird direkt gehalten.

Die Option fällt vollständig an am früheren der folgenden Zeitpunkte: (i) dem ersten Jahrestag des 20. Juni 2025 oder (ii) der nächsten Hauptversammlung der Gesellschaft, vorbehaltlich der fortgesetzten Tätigkeit von Dr. Zbar als Direktor. Die Option hat eine Laufzeit von 10 Jahren mit Ablaufdatum 20. Juni 2035. Nach der Gewährung meldet Dr. Zbar das wirtschaftliche Eigentum an 40.000 derivativen Wertpapieren, ohne Änderungen an seinem Nicht-Derivat-Aktienbesitz.

Die Meldung weist darauf hin, dass die Option von Dr. Zbar allein zugunsten der General Atlantic Service Company, L.P. gehalten wird; er lehnt das wirtschaftliche Eigentum ab, außer im Umfang eines etwaigen pecuniären Interesses.

Es wurden keine Käufe oder Verkäufe von CNTA-Stammaktien oder ADS am offenen Markt gemeldet, und die Meldung weist keine Transaktionen unter einem Rule 10b5-1-Plan aus.

Positive
  • None.
Negative
  • None.

Insights

TL;DR: Routine director option grant for 40k shares at $12.43; minimal dilution, neutral signal for investors.

The Form 4 reveals only a single derivative transaction: a 10-year option covering 40,000 ordinary shares (�40,000 ADSs) at $12.43. No shares were bought or sold in the market. Given CNTA’s ~97 million basic shares outstanding, the potential dilution is <1 bp—immaterial to valuation. The vesting trigger and service requirement are conventional for board compensation and do not suggest a shift in strategic outlook or insider sentiment. Because the director holds the option for the benefit of General Atlantic, the filing appears largely administrative. Investors should view the disclosure as standard governance housekeeping with no immediate earnings or cash-flow impact.

TL;DR: Standard equity incentive aligns director interests; no red flags, neutral corporate-governance impact.

Centessa continues to compensate directors with share-based awards consistent with UK-listed biotech peers. The single-tranche, one-year vesting schedule encourages retention through the next AGM while limiting over-hang. The option’s long expiry matches industry norms and provides alignment without excessive leverage. Disclosure of beneficial ownership disclaimer for General Atlantic is appropriate and transparent. No Rule 10b5-1 plan is cited, indicating flexibility for future transactions. Overall, the filing is procedurally sound and does not materially alter governance risk or shareholder rights.

Centessa Pharmaceuticals plc (CNTA) � Comunicazione interna Form 4

Il direttore Brett I. W. Zbar ha segnalato la concessione di un'opzione per acquisire 40.000 azioni ordinarie di Centessa Pharmaceuticals con scadenza il 20 giugno 2025 ad un prezzo di esercizio di $12,43 per azione. Lo strumento è classificato come “Opzione su azioni (diritto di acquisto)� ed è detenuto direttamente.

L'opzione matura completamente alla prima delle seguenti date: (i) il primo anniversario del 20 giugno 2025 oppure (ii) la successiva assemblea annuale degli azionisti della Società, subordinatamente alla continuazione del servizio del dott. Zbar come direttore. L'opzione ha una durata di 10 anni con scadenza il 20 giugno 2035. Dopo la concessione, il dott. Zbar dichiara la proprietà beneficiaria di 40.000 strumenti derivati senza variazioni nella proprietà diretta delle azioni ordinarie.

Il documento specifica che l'opzione è detenuta dal dott. Zbar esclusivamente per conto di General Atlantic Service Company, L.P.; egli rinuncia alla proprietà beneficiaria salvo per l'interesse pecuniario eventualmente detenuto.

Non sono stati segnalati acquisti o vendite sul mercato aperto di azioni ordinarie CNTA o ADS, né la comunicazione indica transazioni effettuate nell'ambito di un piano Rule 10b5-1.

Centessa Pharmaceuticals plc (CNTA) � Declaración interna Formulario 4

El director Brett I. W. Zbar reportó la concesión de una opción para adquirir 40,000 acciones ordinarias de Centessa Pharmaceuticals con fecha 20 de junio de 2025 a un precio de ejercicio de $12.43 por acción. El instrumento está clasificado como “Opción sobre acciones (derecho a compra)� y se mantiene directamente.

La opción se consolida completamente en la primera de las siguientes fechas: (i) el primer aniversario del 20 de junio de 2025 o (ii) la próxima junta anual de accionistas de la Compañía, condicionada al servicio continuo del Dr. Zbar como director. La opción tiene un plazo de 10 años con fecha de vencimiento el 20 de junio de 2035. Tras la concesión, el Dr. Zbar reporta la propiedad beneficiaria de 40,000 valores derivados sin cambios en la propiedad directa de acciones ordinarias.

El documento señala que la opción es mantenida por el Dr. Zbar únicamente en beneficio de General Atlantic Service Company, L.P.; él renuncia a la propiedad beneficiaria excepto en la medida de cualquier interés pecuniario.

No se reportaron compras o ventas en mercado abierto de acciones ordinarias CNTA o ADS, ni el formulario indica transacciones realizadas bajo un plan Rule 10b5-1.

Centessa Pharmaceuticals plc (CNTA) � 내부� 신고� Form 4

이사 Brett I. W. Zbar� 2025� 6� 20일에 Centessa Pharmaceuticals� 보통� 40,000주를 취득� � 있는 옵션 부�주당 행사 가� $12.43� 보고했습니다. � 권리� '주식 옵션(매수 권리)'으로 분류되며 직접 보유하고 있습니다.

옵션은 (i) 2025� 6� 20일의 1주년 또는 (ii) 회사� 다음 연례 주주총회 � 빠른 날짜� 완전� 취득되며, 이는 Zbar 박사� 이사� 지� 근무� 조건으로 합니�. 옵션� 유효 기간은 10�이며 만료일은 2035� 6� 20일입니다. 부� � Zbar 박사� 40,000개의 파생 증권� 대� 실질 소유�� 보고했으�, 비파� 주식 소유권에� 변동이 없었습니�.

신고서에� � 옵션� Zbar 박사� 의해 General Atlantic Service Company, L.P.� 이익� 위해서만 보유되며, 금전� 이해관계가 있는 범위� 제외하고� 실질 소유권을 부인한다고 명시되어 있습니다.

CNTA 보통주나 ADS� 공개 시장 매수 또는 매도� 보고되지 않았으며, Rule 10b5-1 계획� 따른 거래� 언급되지 않았습니�.

Centessa Pharmaceuticals plc (CNTA) � Déclaration d’initié Formulaire 4

Le directeur Brett I. W. Zbar a déclaré la concession d’une option d’achat de 40 000 actions ordinaires de Centessa Pharmaceuticals au 20 juin 2025 à un prix d’exercice de 12,43 $ par action. L’instrument est classé comme une « Option d’achat d’actions » et est détenu directement.

’oپDz devient entièrement acquise à la première des dates suivantes : (i) le premier anniversaire du 20 juin 2025 ou (ii) la prochaine assemblée générale annuelle de la Société, sous réserve du maintien du service du Dr Zbar en tant que directeur. ’oپDz a une durée de 10 ans avec une date d’expiration au 20 juin 2035. Suite à la concession, le Dr Zbar déclare une propriété bénéficiaire de 40 000 titres dérivés sans changement dans la détention d’actions ordinaires non dérivées.

Le document précise que l’option est détenue par le Dr Zbar uniquement au bénéfice de General Atlantic Service Company, L.P. ; il décline la propriété bénéficiaire, sauf dans la mesure d’un intérêt pécuniaire éventuel.

Aucun achat ou vente sur le marché ouvert d’actions ordinaires CNTA ou d’ADS n’a été signalé, et la déclaration n’indique pas de transactions réalisées dans le cadre d’un plan Rule 10b5-1.

Centessa Pharmaceuticals plc (CNTA) � Insider-Meldung Form 4

Direktor Brett I. W. Zbar meldete die Gewährung einer Option zum Erwerb von 40.000 Stammaktien von Centessa Pharmaceuticals am 20. Juni 2025 zu einem Ausübungspreis von $12,43 pro Aktie. Das Instrument ist als „Aktienoption (Kaufrecht)� klassifiziert und wird direkt gehalten.

Die Option fällt vollständig an am früheren der folgenden Zeitpunkte: (i) dem ersten Jahrestag des 20. Juni 2025 oder (ii) der nächsten Hauptversammlung der Gesellschaft, vorbehaltlich der fortgesetzten Tätigkeit von Dr. Zbar als Direktor. Die Option hat eine Laufzeit von 10 Jahren mit Ablaufdatum 20. Juni 2035. Nach der Gewährung meldet Dr. Zbar das wirtschaftliche Eigentum an 40.000 derivativen Wertpapieren, ohne Änderungen an seinem Nicht-Derivat-Aktienbesitz.

Die Meldung weist darauf hin, dass die Option von Dr. Zbar allein zugunsten der General Atlantic Service Company, L.P. gehalten wird; er lehnt das wirtschaftliche Eigentum ab, außer im Umfang eines etwaigen pecuniären Interesses.

Es wurden keine Käufe oder Verkäufe von CNTA-Stammaktien oder ADS am offenen Markt gemeldet, und die Meldung weist keine Transaktionen unter einem Rule 10b5-1-Plan aus.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
ZBAR BRETT I W

(Last) (First) (Middle)
C/O CENTESSA PHARMACEUTICALS PLC
3RD FLOOR, 1 ASHLEY RD, ALTRINCHAM

(Street)
CHESHIRE X0 WA14 2DT

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Centessa Pharmaceuticals plc [ CNTA ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
06/20/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Share Option (right to buy) $12.43 06/20/2025 A 40,000 (1) 06/20/2035 Ordinary Shares(2) 40,000 $0 40,000 D(3)
Explanation of Responses:
1. The shares subject to such option will vest in full on the earlier of (i) the first anniversary of the grant date or (ii) the Issuer's next annual meeting of shareholders, subject to continued service as a director through the applicable vesting date.
2. The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.
3. The Share Option granted to Dr. Zbar is held by him solely for the benefit of General Atlantic Service Company, L.P. Dr. Zbar disclaims beneficial ownership of the Share Options and the underlying Ordinary Shares, except to the extent of his pecuniary interest therein, if any.
Remarks:
/s/ Iqbal Hussain, attorney-in-fact 06/24/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many Centessa (CNTA) shares are covered by Dr. Zbar’s option grant?

The option covers 40,000 ordinary shares, which may be represented by an equivalent number of ADSs.

What is the exercise price of the newly granted CNTA options?

The exercise (conversion) price is $12.43 per share.

When do the CNTA director options vest?

They vest in full on the earlier of 20 June 2026 or the next Centessa annual meeting, contingent on continued board service.

What is the expiration date of the option reported in this Form 4?

The option expires on 20 June 2035, providing a 10-year exercise window.

Does the filing indicate any open-market purchase or sale of CNTA stock?

No. The Form 4 reports only an option grant; no non-derivative share transactions were disclosed.
Centessa Pharmaceuticals Plc

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2.30B
118.99M
0.49%
94.42%
2.75%
Biotechnology
Pharmaceutical Preparations
United Kingdom
ALTRINCHAM, CHESHIRE