AGÕæÈ˹ٷ½

STOCK TITAN

[Form 4] Centessa Pharmaceuticals plc American Insider Trading Activity

Filing Impact
(Neutral)
Filing Sentiment
(Negative)
Form Type
4
Rhea-AI Filing Summary

Centessa Pharmaceuticals plc (CNTA) reporting person Hussain Iqbal J, General Counsel, executed option exercise and a sale on 08/15/2025. The filing shows the reporting person exercised a share option to acquire 6,000 ordinary shares at an exercise price of $5.84 per share and immediately sold 6,000 ordinary shares at $17.23 per share, leaving 105,386 shares owned directly after the transactions. The Form 4 notes 5,500 ordinary shares are held indirectly by the reporting person’s spouse. The reported sale was effected under a Rule 10b5-1 trading plan adopted on September 14, 2024.

Centessa Pharmaceuticals plc (CNTA), persona che presenta la comunicazione Hussain Iqbal J, General Counsel, ha esercitato opzioni e effettuato una vendita il 15/08/2025. La registrazione indica che la persona ha esercitato un'opzione per acquisire 6.000 azioni ordinarie al prezzo di esercizio di $5,84 per azione e ha immediatamente venduto 6.000 azioni ordinarie a $17,23 per azione, lasciando 105.386 azioni di proprietà diretta dopo le operazioni. Il Modulo 4 segnala che 5.500 azioni ordinarie sono detenute indirettamente dal coniuge della persona che presenta la comunicazione. La vendita riportata è stata eseguita nell'ambito di un piano di trading Rule 10b5-1 adottato il 14 settembre 2024.

Centessa Pharmaceuticals plc (CNTA), persona informante Hussain Iqbal J, Asesor General, realizó el ejercicio de una opción y una venta el 15/08/2025. El informe muestra que la persona ejerció una opción para adquirir 6.000 acciones ordinarias a un precio de ejercicio de $5.84 por acción y vendió inmediatamente 6.000 acciones ordinarias a $17.23 por acción, quedando con 105.386 acciones en propiedad directa tras las transacciones. El Formulario 4 indica que 5.500 acciones ordinarias se mantienen de forma indirecta por el cónyuge de la persona informante. La venta reportada se efectuó bajo un plan de negociación Rule 10b5-1 adoptado el 14 de septiembre de 2024.

Centessa Pharmaceuticals plc (CNTA) ë³´ê³ ì� Hussain Iqbal J, 법무ì´ê´„ì€ 2025-08-15ì—� 옵션 행사 ë°� 매ë„ë¥� 실행했습니다. 제출서류ì—� 따르ë©� ë³´ê³ ì¸ì€ 주당 행사가 $5.84ì—� 보통ì£� 6,000주를 ì·¨ë“하는 옵션ì� 행사하였ê³�, 즉시 보통ì£� 6,000주를 주당 $17.23ì—� 매ë„하여 거래 í›� ì§ì ‘ 보유 주ì‹ì� 105,386ì£� 남았습니ë‹�. Form 4ì—는 ë³´ê³ ì¸ì˜ ë°°ìš°ìžê°€ ê°„ì ‘ì ìœ¼ë¡� 보유í•� 보통ì£� 5,500주가 기재ë˜ì–´ 있습니다. ì‹ ê³ ë� 매ë„ëŠ� 2024ë…� 9ì›� 14ì� 채íƒë� Rule 10b5-1 거래계íšì—� ë”°ë¼ ì´ë£¨ì–´ì¡ŒìŠµë‹ˆë‹�.

Centessa Pharmaceuticals plc (CNTA), personne déclarante Hussain Iqbal J, General Counsel, a effectué l'exercice d'options et une vente le 15/08/2025. Le dépôt indique que la personne a exercé une option pour acquérir 6 000 actions ordinaires au prix d'exercice de 5,84 $ par action et a immédiatement vendu 6 000 actions ordinaires à 17,23 $ par action, laissant 105 386 actions détenues directement après les opérations. Le formulaire 4 précise que 5 500 actions ordinaires sont détenues indirectement par l'époux/épouse de la personne déclarante. La vente rapportée a été réalisée dans le cadre d'un plan de négociation Rule 10b5-1 adopté le 14 septembre 2024.

Centessa Pharmaceuticals plc (CNTA), meldepflichtige Person Hussain Iqbal J, General Counsel, hat am 15.08.2025 Optionsausübung und einen Verkauf vorgenommen. Die Meldung zeigt, dass die Person eine Aktienoption zum Erwerb von 6.000 Stammaktien zum Ausübungspreis von $5,84 je Aktie ausgeübt und unmittelbar 6.000 Stammaktien zu $17,23 je Aktie verkauft hat, sodass nach den Transaktionen 105.386 Aktien direkt gehalten werden. Im Formular 4 wird vermerkt, dass 5.500 Stammaktien indirekt vom Ehepartner der meldenden Person gehalten werden. Der gemeldete Verkauf erfolgte im Rahmen eines Rule-10b5-1-Handelsplans, der am 14. September 2024 angenommen wurde.

Positive
  • Transparent disclosure of exercise and sale details including prices, amounts, and 10b5-1 plan adoption date
  • AGÕæÈ˹ٷ½ized spread between exercise price ($5.84) and sale price ($17.23) for the exercised options
Negative
  • Direct holdings decreased from 111,386 to 105,386 ordinary shares following the sale
  • Insider sold shares (6,000) which may be viewed negatively by some investors despite 10b5-1 plan usage

Insights

TL;DR: Officer exercised options and sold the same number of shares under a pre-existing 10b5-1 plan; net direct holdings modestly reduced.

The transaction is a routine insider exercise of vested options followed by an immediate sale of the acquired shares. The exercise price of $5.84 compared with the sale price of $17.23 indicates the reporting person realized a spread on the exercised options. The filing discloses 111,386 shares before the sale, 105,386 after, and 5,500 indirectly held by a spouse, providing transparent disclosure of insider ownership. This appears procedural and consistent with planned disposition rather than opportunistic timing because the sale was made pursuant to a 10b5-1 plan adopted 09/14/2024.

TL;DR: Disclosure aligns with Section 16 requirements and 10b5-1 safe-harbor usage; no governance red flags in the filing itself.

The Form 4 properly identifies the reporting person’s role (General Counsel and Officer), details the option exercise (6,000 shares exercisable 02/19/2022 through 02/19/2031) and the contemporaneous sale executed under a documented 10b5-1 trading plan. Signatures and explanation footnotes are present. From a governance perspective, the filing meets standard disclosure norms; the presence of a written trading plan reduces concerns about opportunistic insider trading, though the filing does show a reduction in direct holdings.

Centessa Pharmaceuticals plc (CNTA), persona che presenta la comunicazione Hussain Iqbal J, General Counsel, ha esercitato opzioni e effettuato una vendita il 15/08/2025. La registrazione indica che la persona ha esercitato un'opzione per acquisire 6.000 azioni ordinarie al prezzo di esercizio di $5,84 per azione e ha immediatamente venduto 6.000 azioni ordinarie a $17,23 per azione, lasciando 105.386 azioni di proprietà diretta dopo le operazioni. Il Modulo 4 segnala che 5.500 azioni ordinarie sono detenute indirettamente dal coniuge della persona che presenta la comunicazione. La vendita riportata è stata eseguita nell'ambito di un piano di trading Rule 10b5-1 adottato il 14 settembre 2024.

Centessa Pharmaceuticals plc (CNTA), persona informante Hussain Iqbal J, Asesor General, realizó el ejercicio de una opción y una venta el 15/08/2025. El informe muestra que la persona ejerció una opción para adquirir 6.000 acciones ordinarias a un precio de ejercicio de $5.84 por acción y vendió inmediatamente 6.000 acciones ordinarias a $17.23 por acción, quedando con 105.386 acciones en propiedad directa tras las transacciones. El Formulario 4 indica que 5.500 acciones ordinarias se mantienen de forma indirecta por el cónyuge de la persona informante. La venta reportada se efectuó bajo un plan de negociación Rule 10b5-1 adoptado el 14 de septiembre de 2024.

Centessa Pharmaceuticals plc (CNTA) ë³´ê³ ì� Hussain Iqbal J, 법무ì´ê´„ì€ 2025-08-15ì—� 옵션 행사 ë°� 매ë„ë¥� 실행했습니다. 제출서류ì—� 따르ë©� ë³´ê³ ì¸ì€ 주당 행사가 $5.84ì—� 보통ì£� 6,000주를 ì·¨ë“하는 옵션ì� 행사하였ê³�, 즉시 보통ì£� 6,000주를 주당 $17.23ì—� 매ë„하여 거래 í›� ì§ì ‘ 보유 주ì‹ì� 105,386ì£� 남았습니ë‹�. Form 4ì—는 ë³´ê³ ì¸ì˜ ë°°ìš°ìžê°€ ê°„ì ‘ì ìœ¼ë¡� 보유í•� 보통ì£� 5,500주가 기재ë˜ì–´ 있습니다. ì‹ ê³ ë� 매ë„ëŠ� 2024ë…� 9ì›� 14ì� 채íƒë� Rule 10b5-1 거래계íšì—� ë”°ë¼ ì´ë£¨ì–´ì¡ŒìŠµë‹ˆë‹�.

Centessa Pharmaceuticals plc (CNTA), personne déclarante Hussain Iqbal J, General Counsel, a effectué l'exercice d'options et une vente le 15/08/2025. Le dépôt indique que la personne a exercé une option pour acquérir 6 000 actions ordinaires au prix d'exercice de 5,84 $ par action et a immédiatement vendu 6 000 actions ordinaires à 17,23 $ par action, laissant 105 386 actions détenues directement après les opérations. Le formulaire 4 précise que 5 500 actions ordinaires sont détenues indirectement par l'époux/épouse de la personne déclarante. La vente rapportée a été réalisée dans le cadre d'un plan de négociation Rule 10b5-1 adopté le 14 septembre 2024.

Centessa Pharmaceuticals plc (CNTA), meldepflichtige Person Hussain Iqbal J, General Counsel, hat am 15.08.2025 Optionsausübung und einen Verkauf vorgenommen. Die Meldung zeigt, dass die Person eine Aktienoption zum Erwerb von 6.000 Stammaktien zum Ausübungspreis von $5,84 je Aktie ausgeübt und unmittelbar 6.000 Stammaktien zu $17,23 je Aktie verkauft hat, sodass nach den Transaktionen 105.386 Aktien direkt gehalten werden. Im Formular 4 wird vermerkt, dass 5.500 Stammaktien indirekt vom Ehepartner der meldenden Person gehalten werden. Der gemeldete Verkauf erfolgte im Rahmen eines Rule-10b5-1-Handelsplans, der am 14. September 2024 angenommen wurde.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
HUSSAIN IQBAL J

(Last) (First) (Middle)
C/O CENTESSA PHARMACEUTICALS PLC
3RD FL., 1 ASHLEY RD, ALTRINCHAM

(Street)
CHESHIRE X0 WA14 2DT

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Centessa Pharmaceuticals plc [ CNTA ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
X Officer (give title below) Other (specify below)
General Counsel
3. Date of Earliest Transaction (Month/Day/Year)
08/15/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares(1) 08/15/2025 M 6,000 A $5.84 111,386 D
Ordinary Shares(1) 08/15/2025 S(2) 6,000 D $17.23 105,386 D
Ordinary Shares(1) 5,500 I By spouse
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Share Option (right to buy) $5.84 08/15/2025 M 6,000 (3) 02/19/2031 Ordinary Shares(1) 6,000 $0 279,559 D
Explanation of Responses:
1. The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share.
2. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 14, 2024.
3. 25% of the shares subject to such option shall vest and become exercisable on February 19, 2022 and the remaining 75% of the shares subject to such option shall vest and become exercisable in 36 monthly installments on the first day of each month thereafter.
Remarks:
/s/ Richard Menziuso, attorney-in-fact 08/15/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did CNTA insider Hussain Iqbal J report on the Form 4?

The Form 4 reports exercise of 6,000 option shares at $5.84 and sale of 6,000 ordinary shares at $17.23 on 08/15/2025.

Was the sale executed under a 10b5-1 trading plan for CNTA?

Yes. The filing states the sales were effected pursuant to a Rule 10b5-1 trading plan adopted on 09/14/2024.

How many CNTA shares does the reporting person own after the transaction?

The reporting person directly owns 105,386 ordinary shares after the reported transactions, plus 5,500 held indirectly by a spouse.

What were the exercise and sale prices reported?

The option exercise price was $5.84 per share and the sale price was $17.23 per share.

Does the filing indicate vesting terms for the option?

Yes. The option vests 25% on 02/19/2022 and the remaining 75% in 36 monthly installments thereafter; the option expires on 02/19/2031.
Centessa Pharmaceuticals Plc

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Biotechnology
Pharmaceutical Preparations
United Kingdom
ALTRINCHAM, CHESHIRE