Welcome to our dedicated page for Centessa Pharmaceuticals Plc SEC filings (Ticker: CNTA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
SEC documents for a clinical-stage biotech like Centessa Pharmaceuticals can feel like navigating a maze of scientific jargon and risk factors. Pipeline updates on orexin agonists, the LockBody immuno-oncology platform, and critical cash-runway disclosures are scattered across hundreds of pages. Missing one footnote could mean overlooking a trial halt or royalty obligation.
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Adage Capital Management, together with principals Robert Atchinson and Phillip Gross, reports beneficial ownership of 8,403,000 ordinary shares of Centessa Pharmaceuticals, representing 6.29% of the outstanding class based on 133,618,774 shares. The shares are ordinary shares underlying ADSs traded under ticker CNTA. The filing shows no sole voting or dispositive power 鈥� all voting and dispositive rights are reported as shared 鈥� and includes a certification that the securities are held in the ordinary course of business and not for the purpose of changing control. The statement contains ownership details and reporting person roles but does not disclose any transaction terms or plans.
Centessa Pharmaceuticals plc (CNTA) reported interim results through June 30, 2025 showing continued clinical progress and a material licensing transaction. For the six months ended June 30, 2025 the company recorded a net loss of $76.5 million versus $81.9 million in the prior year period, with research and development expense of $76.2 million driven primarily by the OX2R agonist programs. Centessa recognized a $15.0 million upfront payment from a LockBody license to Genmab and constrained additional milestone consideration pending achievement. As of June 30, 2025 the company held $404.1 million of cash, cash equivalents and investments and expects those resources to fund operations into mid-2027. The balance sheet shows $109.5 million of long-term debt and an accumulated deficit of $1.07 billion. Operational updates include ORX750 in an ongoing Phase 2a study, IND clearance and Phase 1 initiation for ORX142, and the prior-phase discontinuation of SerpinPC with related termination charges largely paid down.
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