Helix Acquisition Corp. II and BridgeBio Oncology Therapeutics Announce Effectiveness of Registration Statement for Proposed Business Combination
Helix Acquisition Corp. II (Nasdaq: HLXB) and BridgeBio Oncology Therapeutics (BBOT) announced that their registration statement for their proposed business combination has been declared effective by the SEC. The extraordinary general meeting of Helix shareholders is scheduled for August 4, 2025, with a record date of June 30, 2025.
BBOT is a clinical-stage biopharmaceutical company developing novel small molecule therapeutics targeting RAS and PI3Kα malignancies. The company, originally a subsidiary of BridgeBio Pharma (Nasdaq: BBIO), focuses on improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors. Upon closing, expected in August 2025, the combined company will be renamed "BridgeBio Oncology Therapeutics."
Helix Acquisition Corp. II (Nasdaq: HLXB) e BridgeBio Oncology Therapeutics (BBOT) hanno annunciato che la loro dichiarazione di registrazione per la proposta fusione aziendale Ăš stata approvata dalla SEC. L'assemblea straordinaria degli azionisti di Helix Ăš fissata per il 4 agosto 2025, con data di riferimento al 30 giugno 2025.
BBOT Ăš una societĂ biofarmaceutica in fase clinica che sviluppa nuovi farmaci a piccola molecola mirati alle malignitĂ RAS e PI3Kα. Originariamente una controllata di BridgeBio Pharma (Nasdaq: BBIO), l'azienda si concentra sul miglioramento dei risultati per i pazienti affetti da tumori causati dai due oncogeni piĂč diffusi nei tumori umani. Al completamento della fusione, previsto per agosto 2025, la societĂ combinata assumerĂ il nome "BridgeBio Oncology Therapeutics."
Helix Acquisition Corp. II (Nasdaq: HLXB) y BridgeBio Oncology Therapeutics (BBOT) anunciaron que su declaraciĂłn de registro para la combinaciĂłn empresarial propuesta ha sido declarada efectiva por la SEC. La junta general extraordinaria de accionistas de Helix estĂĄ programada para el 4 de agosto de 2025, con fecha de registro el 30 de junio de 2025.
BBOT es una compañĂa biofarmacĂ©utica en etapa clĂnica que desarrolla nuevos terapĂ©uticos de pequeñas molĂ©culas dirigidos a malignidades RAS y PI3Kα. La empresa, originalmente una subsidiaria de BridgeBio Pharma (Nasdaq: BBIO), se enfoca en mejorar los resultados para pacientes con cĂĄnceres impulsados por los dos oncogenes mĂĄs prevalentes en tumores humanos. Al cierre, esperado para agosto de 2025, la compañĂa combinada se renombrarĂĄ como "BridgeBio Oncology Therapeutics."
Helix Acquisition Corp. II (ëì€ë�: HLXB)ì¶Ä BridgeBio Oncology Therapeutics (BBOT)ê° ì ìë� ìŹì êȰí©ì� ìí ë±ëĄ ìë„ê° SECì� ìíŽ íšë „ì� ë°ìíë€êł� ë°ííì”ëë€. Helix ìŁŒìŁŒë€ì ìì ìŽíë� 2025ë � 8ì� 4ì�ëĄ� ìì ëìŽ ììŒë©�, êž°ì€ìŒì 2025ë � 6ì� 30ìŒì ëë€.
BBOTë� ìì ëšêłì� ë°ìŽì€ì ì� íìŹëĄ�, RAS ë°� PI3Kα ì ì±ìą ìì� íì ìŒëĄ íë ìëĄì� ìë¶ì� ìčëŁì 넌 ê°ë°íêł ìì”ëë€. ì� íìŹë� ìë BridgeBio Pharma (ëì€ë�: BBIO)ì� ìíìŹììŒë©°, ìžê° ìą ììì ê°ì� íí ë� ê°ì ìą ì ì ì ìê° ì ë°íë ì� íìì� ìčëŁ êČ°êłŒ ê°ì ì� ìŁŒë „íêł ìì”ëë€. 2025ë � 8ìëĄ ììëë ê±°ë ìëŁ ì�, í©ëłë� íìŹë� "BridgeBio Oncology Therapeutics"ëĄ� ìŹëȘ ì� ëłêČœí ìì ì ëë�.
Helix Acquisition Corp. II (Nasdaq : HLXB) et BridgeBio Oncology Therapeutics (BBOT) ont annoncé que leur déclaration d'enregistrement pour leur projet de fusion d'entreprise a été déclarée effective par la SEC. L'assemblée générale extraordinaire des actionnaires de Helix est prévue pour le 4 août 2025, avec une date de référence au 30 juin 2025.
BBOT est une société biopharmaceutique en phase clinique développant de nouveaux traitements par petites molécules ciblant les malignités RAS et PI3Kα. Initialement filiale de BridgeBio Pharma (Nasdaq : BBIO), l'entreprise se concentre sur l'amélioration des résultats pour les patients atteints de cancers causés par les deux oncogÚnes les plus répandus dans les tumeurs humaines. à la clÎture, prévue pour août 2025, la société fusionnée sera renommée "BridgeBio Oncology Therapeutics."
Helix Acquisition Corp. II (Nasdaq: HLXB) und BridgeBio Oncology Therapeutics (BBOT) haben bekannt gegeben, dass ihre RegistrierungserklĂ€rung fĂŒr die vorgeschlagene UnternehmenszusammenfĂŒhrung von der SEC fĂŒr wirksam erklĂ€rt wurde. Die auĂerordentliche Hauptversammlung der Helix-AktionĂ€re ist fĂŒr den 4. August 2025 geplant, mit Stichtag am 30. Juni 2025.
BBOT ist ein biopharmazeutisches Unternehmen in der klinischen Phase, das neuartige niedermolekulare Therapeutika entwickelt, die auf RAS- und PI3Kα-Malignome abzielen. Das Unternehmen, ursprĂŒnglich eine Tochtergesellschaft von BridgeBio Pharma (Nasdaq: BBIO), konzentriert sich darauf, die Behandlungsergebnisse fĂŒr Patienten mit Krebsarten zu verbessern, die durch die zwei hĂ€ufigsten Onkogene bei menschlichen Tumoren verursacht werden. Nach dem Abschluss, der fĂŒr August 2025 erwartet wird, wird das kombinierte Unternehmen in "BridgeBio Oncology Therapeutics" umbenannt.
- None.
- Complex regulatory approval process still required for BBOT's clinical programs
- Risk of shareholder redemptions could reduce available capital
- Uncertain timeline for product commercialization
- Multiple clinical trials with uncertain outcomes
Insights
SEC approved merger registration between Helix SPAC and BridgeBio Oncology, with closing expected August 2025 pending shareholder approval.
This press release marks a critical regulatory milestone in the proposed business combination between Helix Acquisition Corp. II (HLXB) and BridgeBio Oncology Therapeutics (BBOT). The SEC's effectiveness declaration for their S-4 registration statement unlocks the path to complete this SPAC merger, with the shareholder vote scheduled for August 4th and expected closing later that month.
The transaction will transform BBOT from a subsidiary of BridgeBio Pharma into an independent, publicly-traded entity focused on a highly specialized oncology niche - developing small molecule therapeutics targeting RAS and PI3Kα malignancies. These represent the two most prevalent oncogenes driving human tumors, addressing substantial unmet medical needs in cancer treatment.
Looking at BBOT's pipeline, they have several clinical-stage assets including the ONKORAS-101 and BREAKER-101 trials, plus three named compounds (BBO-8520, BBO-10203, and BBO-11818) in development. This suggests a diversified approach to their therapeutic targets rather than betting everything on a single candidate.
The SPAC structure provides an alternative path to public markets compared to traditional IPOs, potentially accelerating BBOT's access to capital. Notably, Helix is sponsored by Cormorant Asset Management, a specialized life sciences investor that raised
For existing Helix shareholders, the upcoming extraordinary general meeting represents their decision point - approve the merger or seek redemption of their shares. While the document doesn't disclose valuation details, the post-merger company will retain the BridgeBio Oncology Therapeutics name, suggesting continuity in its scientific mission while gaining the benefits of public market access.
Extraordinary General Meeting of Helix Shareholders Scheduled for August 4, 2025
SOUTH SAN FRANCISCO & BOSTON, July 11, 2025 (GLOBE NEWSWIRE) -- Helix Acquisition Corp. II (â�Helixâ�) (Nasdaq: HLXB), a special purpose acquisition company (â�SPACâ�) sponsored by Cormorant Asset Management, and TheRas, Inc. (d/b/a BridgeBio Oncology Therapeutics) (â�BBOTâ�), a clinical-stage biopharmaceutical company advancing a next-generation pipeline of novel small molecule therapeutics targeting RAS and PI3Kα malignancies, today announced that the registration statement on Form S-4 (File No. 333-288222) (as amended, the â�Registration Statementâ�), filed by Helix and BBOT, relating to the previously-announced business combination among Helix, BBOT, and the other parties thereto (the â�Business Combinationâ�), has been declared effective by the U.S. Securities and Exchange Commission (â�SECâ�).
The extraordinary general meeting of Helix shareholders in connection with the Business Combination (the â�Extraordinary General Meetingâ�) will be held on August 4, 2025. The proxy statement/prospectus relating to the Extraordinary General Meeting will be mailed to Helixâs shareholders of record as of the close of business on the record date of June 30, 2025.
The parties anticipate that the Business Combination will close in August 2025, subject to satisfaction of the conditions to the closing of the Business Combination.
About TheRas, Inc. (d/b/a BridgeBio Oncology Therapeutics) (â�BBOTâ�)
BridgeBio Oncology Therapeutics (BBOT) is a clinical-stage biopharmaceutical company advancing a next-generation pipeline of novel small molecule therapeutics targeting RAS and PI3Kα malignancies. Initially formed as a subsidiary of BridgeBio Pharma, Inc. (Nasdaq: BBIO), BBOT has the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors. For more information, visit .
About Helix Acquisition Corp. II (HLXB) (âHelixâ�)
Helix Acquisition Corp. II (Nasdaq: HLXB) is a special purpose acquisition company (SPAC) formed for the purpose of effecting a merger, capital stock exchange, asset acquisition, stock purchase, reorganization, or similar business combination with one or more businesses. Helix Acquisition Corp. II raised
Additional Information and Where to Find It
As previously disclosed, Helix, BBOT and Helix II Merger Sub., a Delaware corporation and wholly-owned subsidiary of Helix (â�Merger Subâ�), entered into a definitive business combination agreement, dated as of February 28, 2025 (as amended by Amendment No. 1 to the Business Combination Agreement, dated as of June 17, 2025, as it may be further amended, restated, supplemented or otherwise modified from time to time, the â�Business Combination Agreementâ�), pursuant to which, subject to the satisfaction or waiver of the conditions therein, the parties thereto will consummate the Business Combination. Upon closing of the transaction, the company will be renamed âBridgeBio Oncology Therapeuticsâ� (â�PubCoâ�). The Business Combination will be submitted to shareholders of Helix for their consideration. The Registration Statement, which was declared effective by the SEC on July 10, 2025, includes a proxy statement/prospectus that is both the proxy statement of Helix and a prospectus of PubCo relating to the shares to be issued in connection with the Business Combination (the â�Proxy Statement/Prospectusâ�). The definitive Proxy Statement/Prospectus will be mailed to Helixâs shareholders of record as of June 30, 2025, the record date established for voting on the Business Combination. Helix, BBOT and/or PubCo may also file other relevant documents regarding the Business Combination with the SEC. This press release does not contain all the information that should be considered concerning the Business Combination and other matters and is not intended to provide the basis for any investment decision or any other decision in respect of such matters. Before making any voting or investment decision, Helixâs shareholders and other interested persons are urged to read the Proxy Statement/Prospectus and other documents filed in connection with the Business Combination, because these documents will contain important information about Helix, BBOT, PubCo and the Business Combination. Shareholders will also be able to obtain free copies of the Registration Statement, the Proxy Statement/Prospectus and other documents filed with the SEC, once available, without charge, at the SECâs website located at , or by directing a request to Helix Acquisition Corp. II, c/o Cormorant Asset Management, LP, 200 Clarendon Street, 52nd Floor, Boston, MA 02116.
Participants in the Solicitation
Helix, BBOT, and their directors and executive officers and other persons may be deemed to be participants in the solicitations of proxies from Helixâs shareholders in respect of the Business Combination and the other matters set forth in the Registration Statement. A list of the names of such persons, and information regarding their interests in the Business Combination and their ownership of Helixâs and BBOTâs securities are contained in the Proxy Statement/Prospectus. The Proxy Statement/Prospectus may be obtained free of charge at the SECâs website located at www.sec.gov, or by directing a request to Helix Acquisition Corp. II, c/o Cormorant Asset Management, LP, 200 Clarendon Street, 52nd Floor, Boston, MA 02116.
Forward-Looking Statements
Certain statements included in this press release that are not historical facts are forward-looking statements. Forward-looking statements generally are accompanied by words such as âbelieve,â� âmay,â� âwill,â� âestimate,â� âcontinue,â� âanticipate,â� âintend,â� âexpect,â� âshould,â� âwould,â� âplan,â� âpredict,â� âpotential,â� âseem,â� âseek,â� âfuture,â� âoutlookâ� and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding estimates and forecasts of other financial and performance metrics and projections of market opportunity; expectations and timing related to the success, cost and timing of product development activities, including timing of initiation, completion and data readouts for clinical trials and the potential approval of BBOTâs product candidates, including the progress and results of the ONKORAS-101 and BREAKER-101 clinical trials and the expected dosing of the first patient with BBO-11818; the clinical and therapeutic potential of BBO-8520, BBO-10203 and BBO-11818; the size and growth potential of the markets for BBOTâs product candidates; the therapeutic and curative potential of BBOTâs product candidates; financing and other business milestones; potential benefits of the business combination; and expectations relating to the business combination, including the proceeds of the business combination and the financing and BBOTâs expected cash runway and the timing of the closing of the business combination. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of BBOTâs and Helixâs management and are not predictions of actual performance. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as and must not be relied on by an investor as a guarantee, an assurance, a prediction, or a definitive statement of fact or probability. Actual events and circumstances are difficult or impossible to predict and may differ from assumptions. Many actual events and circumstances are beyond the control of BBOT and Helix. These forward-looking statements are subject to a number of risks and uncertainties, including changes in domestic and foreign business, market, financial, political, and legal conditions; the inability of the parties to successfully or timely enter into definitive agreements with respect to the business combination or consummate the business combination, including the risk that any regulatory approvals are not obtained, are delayed or are subject to unanticipated conditions (such as any SEC statements or enforcements or other actions relating to SPACs) that could adversely affect the combined company or the expected benefits of the business combination, or the risk that the approval of the shareholders of Helix or any other condition to closing is not obtained; failure to realize the anticipated benefits of the business combination; risks relating to any legal proceedings that may be instituted against Helix, the combined company or others following the announcement of the business combination, risks relating to the uncertainty of the projected financial information with respect to BBOT and the combined company; risks related to the approval of BBOTâs product candidates and the timing of expected regulatory and business milestones; ability to negotiate definitive contractual arrangements with potential customers; the impact of competitive product candidates; ability to obtain sufficient supply of materials; global economic and political conditions; the effects of competition on BBOTâs future business; the amount of redemption requests made by Helixâs public shareholders; and those factors discussed in documents Helix has filed or will file with the SEC. Additional risks related to BBOTâs business include, but are not limited to: uncertainty regarding outcomes of BBOTâs ongoing clinical trials, particularly as they relate to regulatory review and potential approval for its product candidates; risks associated with BBOTâs efforts to commercialize its product candidates; BBOTâs ability to maintain its existing agreements with third parties and to negotiate and enter into new definitive agreements on favorable terms, if at all; the impact of competing product candidates on BBOTâs business; intellectual property-related claims; BBOTâs ability to attract and retain qualified personnel; and BBOTâs ability to source the raw materials for its product candidates.
If any of these risks materialize or Helixâs or BBOTâs assumptions prove incorrect, actual results could differ materially from the results implied by these forward-looking statements. There may be additional risks that neither Helix or BBOT presently know or that Helix and BBOT currently believe are immaterial that could also cause actual results to differ from those contained in the forward-looking statements. In addition, forward-looking statements reflect Helixâs and BBOTâs expectations, plans, or forecasts of future events and views as of the date of this press release and are qualified in their entirety by reference to the cautionary statements herein. Helix and BBOT anticipate that subsequent events and developments will cause Helixâs and BBOTâs assessments to change. These forward-looking statements should not be relied upon as representing Helixâs and BBOTâs assessments as of any date subsequent to the date of this press release. Accordingly, undue reliance should not be placed upon the forward-looking statements. Neither Helix, BBOT, nor any of their respective affiliates undertake any obligation to update these forward-looking statements, except as required by law.
No Offer or Solicitation
This press release shall not constitute a solicitation of a proxy, consent or authorization with respect to any securities or in respect of the business combination, or an offer to sell, or the solicitation of an offer to buy, any securities. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended, or an exemption therefrom, nor shall any sale of securities in any states or jurisdictions in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction be affected. Neither the SEC nor any securities commission of any other U.S. or non-U.S. jurisdiction has approved or disapproved of the business combination contemplated hereby or determined that this press release is truthful or complete. Any representation to the contrary is a criminal offense.
BridgeBio Oncology Therapeutics Contact:Â
Idan Elmelech
Senior Vice President, Strategy & Business Development
(650) 405-7021
Helix Acquisition Corp. II Contact:Â
Caleb Tripp
Chief Financial Officer
(857) 702-0370
