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Actuate Therapeutics Announces Proposed Public Offering of Common Stock

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Actuate Therapeutics (NASDAQ: ACTU), a clinical-stage biopharmaceutical company developing cancer therapies through GSK-3β inhibition, has announced a proposed public offering of common stock. The company plans to grant underwriters a 30-day option to purchase an additional 15% of shares at the public offering price, less underwriting discounts.

The offering, managed by Lucid Capital Markets as sole book-running manager, will be conducted under an effective S-3 shelf registration. Proceeds will be used for working capital and general corporate purposes. The completion and terms of the offering are subject to market conditions.

Actuate Therapeutics (NASDAQ: ACTU), società biofarmaceutica in fase clinica che sviluppa terapie oncologiche tramite l'inibizione della GSK-3β, ha annunciato una proposta di offerta pubblica di azioni ordinarie. L'azienda intende concedere agli sottoscrittori un opzione di 30 giorni per acquistare un ulteriore 15% delle azioni al prezzo dell'offerta pubblica, al netto degli sconti di sottoscrizione.

L'offerta, con Lucid Capital Markets in qualità di unico book-running manager, sarà effettuata in base a un modulo S-3 già efficace. I proventi saranno destinati al capitale circolante e a scopi societari generali. Il perfezionamento e i termini dell'operazione dipendono dalle condizioni di mercato.

Actuate Therapeutics (NASDAQ: ACTU), una compañía biofarmacéutica en fase clínica que desarrolla terapias contra el cáncer mediante la inhibición de GSK-3β, ha anunciado una propuesta de oferta pública de acciones ordinarias. La empresa planea otorgar a los colocadores una opción de 30 días para comprar un 15% adicional de las acciones al precio de la oferta pública, menos los descuentos de suscripción.

La oferta, gestionada por Lucid Capital Markets como único book-running manager, se realizará bajo un registro S-3 efectivo. Los ingresos se destinarán a capital de trabajo y a propósitos corporativos generales. La ejecución y los términos de la oferta están sujetos a las condiciones del mercado.

Actuate Therapeutics (NASDAQ: ACTU)� GSK-3β 억제� 통해 � 치료제를 개발하는 임상 단계� 바이오제� 기업으로, 보통� 공개 매도� 제안했다� 발표했습니다. 회사� 인수인에� 공개 매도 가격에� 인수 수수료를 공제� 금액으로 추가 주식� 15%� 매수� � 있는 30� 옵션� 부여할 계획입니�.

이번 공모� 단독 북러� 매니저� Lucid Capital Markets가 주관하며, 효력� 있는 S-3 서류� 따라 진행됩니�. 수익금은 운전자본 � 일반 기업 목적� 사용� 예정입니�. 공모� 완료 여부와 구체� 조건은 시장 상황� 따라 달라집니�.

Actuate Therapeutics (NASDAQ: ACTU), une société biopharmaceutique en phase clinique développant des traitements contre le cancer via l'inhibition de la GSK�3β, a annoncé une offre publique proposée d'actions ordinaires. La société prévoit d'accorder aux teneurs d'ordre une option de 30 jours pour acheter 15% supplémentaires des actions au prix de l'offre publique, déduction faite des décotes de souscription.

L'opération, placée par Lucid Capital Markets en tant qu'unique book‑running manager, sera réalisée dans le cadre d'un enregistrement S�3 effectif. Les produits seront utilisés pour le fonds de roulement et des besoins généraux de la société. La réalisation et les modalités de l'offre dépendront des conditions du marché.

Actuate Therapeutics (NASDAQ: ACTU), ein biopharmazeutisches Unternehmen in der klinischen Phase, das Krebsbehandlungen durch GSK�3β‑Hemmung entwickelt, hat eine vorgeschlagene öffentliche Platzierung von Stammaktien angekündigt. Das Unternehmen beabsichtigt, den Underwritern eine 30‑tägige Option zum Kauf von zusätzlichen 15% der Aktien zum Ausgabepreis abzüglich Underwriting‑Rabatten zu gewähren.

Die Emission, bei der Lucid Capital Markets als alleiniger Book‑Running‑Manager fungiert, wird unter einer wirksamen S�3‑Prospektregistrierung durchgeführt. Die Erlöse sollen für das Working Capital und allgemeine Unternehmenszwecke verwendet werden. Abschluss und Bedingungen der Platzierung hängen von den Marktbedingungen ab.

Positive
  • Potential to strengthen working capital position through the offering
  • Effective S-3 shelf registration already in place
  • Established underwriter Lucid Capital Markets managing the offering
Negative
  • Potential dilution for existing shareholders
  • Uncertainty regarding offering completion and final terms
  • Stock price may face pressure due to increased share supply

Insights

Actuate Therapeutics' stock offering will dilute existing shareholders while raising capital for their cancer drug development pipeline.

Actuate Therapeutics (NASDAQ: ACTU) has announced plans for a public offering of common stock, which signals the company's need to raise additional capital. This secondary offering will have a dilutive effect on existing shareholders, as new shares will be added to the market. The magnitude of dilution remains unknown since the offering size hasn't been disclosed.

The company is also granting underwriters a standard 15% overallotment option (greenshoe), which could further increase the offering size if market demand is strong. The proceeds will be used for working capital and general corporate purposes rather than a specific strategic initiative, suggesting the funds may primarily support ongoing operations and research programs.

As a clinical-stage biopharmaceutical company without marketable products, Actuate likely requires continuous capital infusions to fund its GSK-3β inhibitor development programs targeting difficult-to-treat cancers. This offering follows the typical financing pattern for pre-revenue biotech companies, which often tap public markets periodically to extend their operational runway.

The company has filed a shelf registration (Form S-3), indicating they've been planning this capital raise. With Lucid Capital Markets as the sole book-runner, this appears to be a relatively modest offering without a large banking syndicate, which is typical for smaller biotech financings.

CHICAGO and FORT WORTH, Texas, Sept. 09, 2025 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate� or the “Company�), a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers through the inhibition of glycogen synthase kinase-3 beta (GSK-3β), today announced that it intends to offer and sell shares of its common stock in an underwritten public offering. The Company also expects to grant the underwriters a 30-day option to purchase up to an additional fifteen percent (15%) of shares of its common stock offered in the public offering at the public offering price per share, less underwriting discounts and commissions. The offering is subject to market conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

The Company intends to use the net proceeds from the proposed offering for working capital and general corporate purposes.

Lucid Capital Markets is acting as sole book-running manager for the offering.

The common stock described above is being offered by the Company pursuant to a shelf registration statement on Form S-3 (File No. 333-), including a base prospectus, previously filed with and subsequently declared effective by the Securities and Exchange Commission (the “SEC�). A preliminary prospectus supplement relating to the offering has been filed with the SEC and is available on the SEC’s website at . A final prospectus supplement describing the terms of the offering will be filed with the SEC. The offering will be made only by means of the prospectus supplement and the accompanying base prospectus, as may be further supplemented by any free writing prospectus and/or pricing supplement that the Company may file with the SEC. Copies of the preliminary prospectus supplement, and accompanying base prospectus relating to this offering, may be obtained from Lucid Capital Markets, LLC, 570 Lexington Avenue, 40th Floor, New York, NY 10022.

This press release shall not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Actuate Therapeutics, Inc.

Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers. Actuate’s lead investigational drug, elraglusib (a novel GSK-3β inhibitor), targets molecular pathways in cancer that are involved in promoting tumor growth and resistance to conventional cancer drugs such as chemotherapy through the inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) and DNA Damage Response (DDR). Elraglusib may also mediate anti-tumor immunity through the regulation of multiple immune checkpoints and immune cell function. For additional information, please visit the Company’s website at http://www.actuatetherapeutics.com.

Forward Looking Statements

This press release contains forward-looking statements under the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, including statements regarding Actuate’s expectations on the timing and completion of the offering and the anticipated use of proceeds therefrom. The offering is subject to market and other conditions and there can be no assurance as to whether or when the offering may be completed or as to the actual size or terms of the offering. Forward-looking statements involve known and unknown risks, uncertainties and other factors that could cause actual results to differ materially, including those risks disclosed under the caption “Risk Factors� in the preliminary prospectus supplement related to the offering. These forward-looking statements speak only as of the date hereof. Actuate does not undertake and specifically disclaims any obligation to update or revise such statements to reflect new circumstances or unanticipated events as they occur, except as required by law.

Investor Contact

Mike Moyer
Managing Director
LifeSci Advisors, LLC
[email protected]

Media Contact

Ignacio Guerrero-Ros, Ph.D., or David Schull
Russo Partners, LLC
[email protected]
[email protected]
(858) 717-2310 or (646) 942-5604


FAQ

What is the purpose of Actuate Therapeutics' (ACTU) public stock offering?

The offering aims to raise funds for working capital and general corporate purposes. The exact size and terms are subject to market conditions.

How much additional stock can underwriters purchase in ACTU's offering?

Underwriters will have a 30-day option to purchase up to an additional 15% of shares at the public offering price, less underwriting discounts and commissions.

Who is managing Actuate Therapeutics' (ACTU) public offering?

Lucid Capital Markets is acting as the sole book-running manager for the offering.

What is Actuate Therapeutics' main focus as a company?

Actuate is a clinical-stage biopharmaceutical company focused on developing therapies for high-impact, difficult-to-treat cancers through the inhibition of glycogen synthase kinase-3 beta (GSK-3β).

How can investors access the prospectus for ACTU's stock offering?

Investors can access the preliminary prospectus supplement on the SEC's website or obtain copies from Lucid Capital Markets.
Actuate Therapeutics Inc

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164.72M
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Biotechnology
Pharmaceutical Preparations
United States
FORT WORTH